MOTS-C
MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) is a 16-amino-acid peptide encoded within the mitochondrial genome that regulates metabolism and insulin sensitivity. It acts as a signaling molecule, primarily targeting skeletal muscle to improve glucose metabolism and protect against age- and diet-dependent insulin resistance and obesity. Its levels in the body typically decrease with age, but increase in response to exercise.
Price range: $59.99 through $159.99
For research use only. Not for human consumption. Not FDA approved.
About this compound
MOTS-C is a 16-amino acid peptide encoded within the mitochondrial 12S rRNA gene, representing a class of mitochondria-derived peptides (MDPs) that function as retrograde signaling molecules between mitochondria and the nucleus.
Compound Specifications
- Sequence: MRWQEMGYIFYPRKLR
- Molecular Formula: C₁₀₆H₁₇₃N₃₅O₂₄S
- Molecular Weight: 2,174.80 Da
- CAS: 1627580-50-0
- Form: Lyophilized powder
- Storage: −20°C, protected from light and moisture
- Reconstitution: Sterile water or PBS
Research Context
MOTS-C is studied in the context of AMPK activation, glucose metabolism, mitochondrial biogenesis signaling, and metabolic stress response pathways.
For research and laboratory use only. Not for human or animal consumption. Research Use Only.
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